Allergies and Asthma
Explore the immune system’s role in allergic asthma.
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Overview
As with most allergic responses, the immune system plays a role in allergic asthma. Allergic asthma occurs when an allergen triggers the immune system to cause inflammation in the airways of the lungs. Both medication and avoiding allergens can help to manage asthma. Talk to a doctor or visit a health clinic to learn more about options for you or your child.
Key Points
- Asthma is caused when the immune system activates inflammation in the airways of the lungs, causing them to narrow and making it difficult to breathe.
- Allergic asthma is when an allergen triggers the immune system to activate inflammation in the lungs.
The Immune System and Asthma
Asthma occurs when the immune system is triggered to cause inflammation in the airways of the lungs. The rapid inflammation causes the airways to narrow leading to shortness of breath, wheezing, coughing, and chest tightness. Inflammation is a normal part of many immune responses. The immune system induces an inflammatory response causing tissues and blood vessels to swell, allowing immune cells to get to the site of infection or injury. While inflammation is essential for many immune responses, it can also cause damage or if the immune system overreacts.
In people with asthma, the immune system overreacts to environmental triggers that are generally of little to no harm to the human body, causing excess inflammation in the airways of the lungs. Asthma can be triggered by allergens, exercise, stress, respiratory viruses, and more.
Allergic Asthma
Allergic or atopic asthma is the most common cause of asthma. The onset of an asthma attack in people with allergies starts much the same way as other triggers of asthma. Airborne allergens such as pollen or pet dander, are breathed in and trigger an immune response. This immune response triggers typical allergy symptoms like sneezing, watery eyes, runny nose. However, in some people the immune response also triggers immune cells to accumulate in the lungs, triggering inflammation, and causing asthma symptoms.
Both medication and avoiding allergens can help to manage asthma. Talk to a doctor or visit a health clinic to learn more about options for you.
Sources
- Jain, A., Marshall, J., Buikema, A., Bancroft, T., Kelly, J. P., & Newschaffer, C. J. (2015). Autism Occurrence by MMR Vaccine Status Among US Children With Older Siblings With and Without Autism. JAMA, 313(15), 1534. https://doi.org/10.1001/jama.2015.3077
- Taylor, B., Miller, E., Farrington, Cp., Petropoulos, M.-C., Favot-Mayaud, I., Li, J., & Waight, P. A. (1999). Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association. The Lancet, 353(9169), 2026–2029. https://doi.org/10.1016/s0140-6736(99)01239-8
- Madsen, K. M., Hviid, A., Vestergaard, M., Schendel, D., Wohlfahrt, J., Thorsen, P., Olsen, J., & Melbye, M. (2002). A Population-Based Study of Measles, Mumps, and Rubella Vaccination and Autism. New England Journal of Medicine, 347(19), 1477–1482. https://doi.org/10.1056/nejmoa021134
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